WO2008090555A3 - Medical devices having a matrix adhered thereof - Google Patents

Medical devices having a matrix adhered thereof Download PDF

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Publication number
WO2008090555A3
WO2008090555A3 PCT/IL2008/000104 IL2008000104W WO2008090555A3 WO 2008090555 A3 WO2008090555 A3 WO 2008090555A3 IL 2008000104 W IL2008000104 W IL 2008000104W WO 2008090555 A3 WO2008090555 A3 WO 2008090555A3
Authority
WO
WIPO (PCT)
Prior art keywords
medical devices
matrix
matrix adhered
adhered
adherence
Prior art date
Application number
PCT/IL2008/000104
Other languages
French (fr)
Other versions
WO2008090555A2 (en
Inventor
Abraham Jackob Domb
Yulia Shaulov
Yair Levi
Daniel Mandler
Noam Tal
Original Assignee
Elutex Ltd
Abraham Jackob Domb
Yulia Shaulov
Yair Levi
Daniel Mandler
Noam Tal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elutex Ltd, Abraham Jackob Domb, Yulia Shaulov, Yair Levi, Daniel Mandler, Noam Tal filed Critical Elutex Ltd
Publication of WO2008090555A2 publication Critical patent/WO2008090555A2/en
Publication of WO2008090555A3 publication Critical patent/WO2008090555A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09DCOATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D5/00Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
    • C09D5/44Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes for electrophoretic applications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F2/00Processes of polymerisation
    • C08F2/58Polymerisation initiated by direct application of electric current
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F285/00Macromolecular compounds obtained by polymerising monomers on to preformed graft polymers
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F291/00Macromolecular compounds obtained by polymerising monomers on to macromolecular compounds according to more than one of the groups C08F251/00 - C08F289/00
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L51/00Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers
    • C08L51/003Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Compositions of derivatives of such polymers grafted on to macromolecular compounds obtained by reactions only involving unsaturated carbon-to-carbon bonds
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09DCOATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D151/00Coating compositions based on graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers
    • C09D151/003Coating compositions based on graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bonds; Coating compositions based on derivatives of such polymers grafted on to macromolecular compounds obtained by reactions only involving unsaturated carbon-to-carbon bonds
    • CCHEMISTRY; METALLURGY
    • C09DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09DCOATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D5/00Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes
    • C09D5/44Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes for electrophoretic applications
    • C09D5/4476Coating compositions, e.g. paints, varnishes or lacquers, characterised by their physical nature or the effects produced; Filling pastes for electrophoretic applications comprising polymerisation in situ

Abstract

Medical devices having a matrix comprising a pharmaceutically active agent, the matrix being adhered to a surface of the medical device via an adherence, are disclosed herein, as well as methods of utilizing the adherence to modulate a release of the pharmaceutically active agent.
PCT/IL2008/000104 2007-01-22 2008-01-22 Medical devices having a matrix adhered thereof WO2008090555A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88146807P 2007-01-22 2007-01-22
US60/881,468 2007-01-22

Publications (2)

Publication Number Publication Date
WO2008090555A2 WO2008090555A2 (en) 2008-07-31
WO2008090555A3 true WO2008090555A3 (en) 2009-01-08

Family

ID=39296014

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/IL2008/000104 WO2008090555A2 (en) 2007-01-22 2008-01-22 Medical devices having a matrix adhered thereof
PCT/IL2008/000103 WO2008090554A2 (en) 2007-01-22 2008-01-22 Modified conductive surfaces prepared by electrografting of diazonium salts

Family Applications After (1)

Application Number Title Priority Date Filing Date
PCT/IL2008/000103 WO2008090554A2 (en) 2007-01-22 2008-01-22 Modified conductive surfaces prepared by electrografting of diazonium salts

Country Status (1)

Country Link
WO (2) WO2008090555A2 (en)

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EP2259803B2 (en) 2008-02-29 2019-03-13 Ferrosan Medical Devices A/S Device for promotion of hemostasis and/or wound healing
GB0816783D0 (en) 2008-09-15 2008-10-22 Carmeda Ab Immobilised biological entities
EP2391401A2 (en) 2009-02-02 2011-12-07 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Crystalline drug-containing coatings
WO2010119443A1 (en) * 2009-04-13 2010-10-21 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Process for electrochemical coating of conductive surfaces by organic nanoparticles
GB201004101D0 (en) 2010-03-12 2010-04-28 Carmeda Ab Immobilised biological entities
JP5645494B2 (en) * 2010-06-16 2014-12-24 帝人株式会社 Method for producing amine body
IN2014DN08122A (en) 2012-03-06 2015-05-01 Ferrosan Medical Devices As
CN102657900A (en) * 2012-04-10 2012-09-12 微创医疗器械(上海)有限公司 Medicine balloon based on hydrogen bond effects and coating method thereof
EP2977066A3 (en) 2012-06-12 2016-07-27 Ferrosan Medical Devices A/S Dry haemostatic composition
EP2674173A1 (en) * 2012-06-15 2013-12-18 Commissariat A L'energie Atomique Et Aux Energies Alternatives Implantable material grafted with a cell antiproliferative and/or antibacterial film and process of grafting thereof
EP2813249A1 (en) 2013-06-14 2014-12-17 Biowintech Implantable material grafted with a cell antiproliferative and/or antibacterial film synthetized from a bifunctional molecule
CA2912357C (en) 2013-06-21 2019-12-31 Ferrosan Medical Devices A/S Vacuum expanded dry composition and syringe for retaining same
EP3079731B1 (en) 2013-12-11 2018-08-08 Ferrosan Medical Devices A/S Dry composition comprising an extrusion enhancer
US9593080B1 (en) 2014-06-11 2017-03-14 The Arizona Board Of Regents On Behalf Of The University Of Arizona Triazabutadienes as cleavable cross-linkers
US10047061B2 (en) 2014-06-11 2018-08-14 Arizona Board Of Regents On Behalf Of The University Of Arizona Water-soluble triazabutadienes
US10125105B2 (en) 2014-06-11 2018-11-13 Arizona Board Of Regents On Behalf Of The University Of Arizona Triazabutadienes as cleavable cross-linkers
US11046818B2 (en) 2014-10-13 2021-06-29 Ferrosan Medical Devices A/S Dry composition for use in haemostasis and wound healing
CN107206165B (en) 2014-12-24 2020-10-23 弗罗桑医疗设备公司 Syringe for holding and mixing first and second substances
RU2717356C2 (en) 2015-07-03 2020-03-23 Ферросан Медикал Дивайсиз А/С Syringe for holding vacuum in storage state
US10472330B2 (en) 2015-08-11 2019-11-12 Arizona Board Of Regents On Behalf Of The University Of Arizona Substituted triazenes protected from degradation by carboxylation of N1
US10954195B2 (en) 2015-08-11 2021-03-23 Arizona Board Of Regents On Behalf Of The University Of Arizona Substituted triazenes protected from degradation by carboxylation of N1
CN106146801A (en) * 2016-07-04 2016-11-23 武汉工程大学 New compound four [(p-aminophenyl epoxide) methyl] methane as firming agent in the application of epoxy-resin systems
US11339129B2 (en) 2016-07-29 2022-05-24 Arizona Board of Regents on behalf of the University of Arizon Triazabutadienes as cleavable cross-linkers
US11801324B2 (en) 2018-05-09 2023-10-31 Ferrosan Medical Devices A/S Method for preparing a haemostatic composition

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FR2766092A1 (en) * 1997-07-16 1999-01-22 Centre Nat Rech Scient IMPLANTABLE DEVICE COATED WITH A POLYMER CAPABLE OF RELEASING BIOLOGICALLY ACTIVE SUBSTANCES
WO2001039813A1 (en) * 1999-12-03 2001-06-07 Efrat Biopolymers Ltd. Electropolymerizable monomers and polymeric coatings on implantable devices
FR2862879A1 (en) * 2003-11-27 2005-06-03 Alchimer S A ORGANIC BIOACTIVE COATINGS APPLICABLE TO VASCULAR STENTS
US20050255631A1 (en) * 2002-08-26 2005-11-17 Commissariat A L'energie Atomique Method of soldering a polymer surface to a conducting or semiconducting surface and applications of same
WO2006008739A2 (en) * 2004-07-19 2006-01-26 Elutex Ltd. Modified conductive surfaces having active substances attached thereto
WO2007024500A1 (en) * 2005-08-25 2007-03-01 Medtronic Vascular, Inc. Controlled radical polymerization-derived block copolymer compositions for medical device coatings

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FR2829046B1 (en) * 2001-08-28 2005-01-14 Commissariat Energie Atomique METHOD OF GRAFTING AND GROWING A CONDUCTIVE ORGANIC FILM ON A SURFACE
FR2860523B1 (en) * 2003-10-01 2006-01-13 Commissariat Energie Atomique METHOD FOR FORMING POLYMER FILM ON A CONDUCTIVE OR SEMICONDUCTOR SURFACE OF ELECTRICITY BY ELECTRO-GRAFTING, SURFACES OBTAINED AND APPLICATIONS
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Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2766092A1 (en) * 1997-07-16 1999-01-22 Centre Nat Rech Scient IMPLANTABLE DEVICE COATED WITH A POLYMER CAPABLE OF RELEASING BIOLOGICALLY ACTIVE SUBSTANCES
WO2001039813A1 (en) * 1999-12-03 2001-06-07 Efrat Biopolymers Ltd. Electropolymerizable monomers and polymeric coatings on implantable devices
US20050255631A1 (en) * 2002-08-26 2005-11-17 Commissariat A L'energie Atomique Method of soldering a polymer surface to a conducting or semiconducting surface and applications of same
FR2862879A1 (en) * 2003-11-27 2005-06-03 Alchimer S A ORGANIC BIOACTIVE COATINGS APPLICABLE TO VASCULAR STENTS
WO2006008739A2 (en) * 2004-07-19 2006-01-26 Elutex Ltd. Modified conductive surfaces having active substances attached thereto
WO2007024500A1 (en) * 2005-08-25 2007-03-01 Medtronic Vascular, Inc. Controlled radical polymerization-derived block copolymer compositions for medical device coatings

Also Published As

Publication number Publication date
WO2008090555A2 (en) 2008-07-31
WO2008090554A3 (en) 2008-12-18
WO2008090554A2 (en) 2008-07-31

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